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RNAi Experiment: [cgc5655]:E04F6.3 Ace View of [cgc5655]:E04F6.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  E04F6.3 (maoc-1)
Description of "E04F6.3"  E04F6.3 encodes a protein that is orthologous (with 52% identity over 93% of its length) to residues 334-609 of human 17-BETA-HYDROXYSTEROID DEHYDROGENASE IV (HSD17B4; OMIM:601860, mutated in D-bifunctional protein deficiency), a protein of 736 residues whose N- and C-terminal domains are orthologous to DHS-28; E04F6.3 contains a MaoC-like domain, found in diverse enzymes (HSD17B4, peroxisomal hydratase-dehydrogenase-epimerase, and the fatty acid synthase beta subunit); E04F6.3 has no obvious function in mass RNAi assays.
KOG Annotation  Peroxisomal multifunctional beta-oxidation protein and related enzymes
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:7196410..7197299)
Transcript overlap: 781 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 718
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "E04F6.3" Links  Wormbase NCBI
[cgc5655]:E04F6.3 Phenotypes Help with Phenotypes
Phenotype  Unclassified lipid metabolism abnormal
[cgc5655]:E04F6.3 Experiment Details Ace View
Laboratory  GR
RNAi Reagent & Type  sjj_E04F6.3 (PCR_reagent)
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
Delivery Method  Bacterial_feeding
Date  2003-1-10
Gene Plot of E04F6.3 Browse using GBrowse
Gene Graph