RNAi Experiment: [cgc5655]:daf-2:F11E6.5 |
Ace View of [cgc5655]:daf-2:F11E6.5
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Genes Inhibited |
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Gene Inhibited |
F11E6.5 (elo-2) |
Description of "F11E6.5" |
The elo-2 gene encodes a palmitic acid elongase, homologous to polyunsaturated fatty acid (PUFA) elongases such as ELO-1, that is required for normally rapid growth, normally large body size, fertility, and for the quantitative regulation of the ultradian defecation rhythm; the joint action of ELO-2 with ELO-1 is strongly required for 20-carbon PUFA production and for general viability; elo-2 is most strongly expressed in intestinal cells, as well as other tissues such as the ventral nerve cord, pharyngeal muscles, uterus, and tail. |
KOG Annotation  |
Long chain fatty acid elongase
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (IV:17466273..17467373)
Transcript overlap: 781 nt |
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Sliding Window |
Raw score: 676
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F11E6.5" Links |
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[cgc5655]:daf-2:F11E6.5 Phenotypes |
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Phenotype |
Unclassified
lipid metabolism abnormal
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[cgc5655]:daf-2:F11E6.5 Experiment Details |
Ace View |
Laboratory |
GR |
RNAi Reagent & Type |
sjj_F11E6.5 (PCR_reagent) |
Strain |
daf-2(e1370) |
Reference |
Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." |
Delivery Method |
Bacterial_feeding |
Date |
2003-1-10 |
Gene Plot of F11E6.5 |
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