Link to C47D12.7Link to C47D12.6b.4Link to C47D12.6b.2Link to C47D12.6b.1Link to C47D12.6b.3Link to C47D12.6aLink to C47D12.6b.5Link to C47D12.8RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to C47D12.7Link to C47D12.6b.2Link to C47D12.6b.1Link to C47D12.6b.3Link to C47D12.6b.4Link to C47D12.6aLink to C47D12.6b.5RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: [cgc5655]:tph-1:C47D12.7 Ace View of [cgc5655]:tph-1:C47D12.7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C47D12.7 (kel-1)
Description of "C47D12.7"  kel-1 encodes a BTB/POZ- and Kelch motif-containing protein orthologous to Drosophila Kelch, which is essential for actin organization in ovarian ring canals; in C. elegans, kel-1 is required for regulating feeding during larval development and more specifically, for pharyngeal isthmus peristalsis and efficient trapping of food in the pharynx; KEL-1 is first expressed at the 1.5-fold stage of embryogenesis in the pharyngeal lumen and the nerve ring; later adult and larval expression is confined to the pharyngeal gland cells in which KEL-1 may be required for maintenance of gland cell-specific structures.
KOG Annotation  Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:11690251..11691273)
Transcript overlap: 764 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 619
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C47D12.7" Links  Wormbase NCBI
Gene Inhibited  C47D12.6 (trs-1)
Description of "C47D12.6"  This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial.
Evidence for Inhibition 
ePCR Transcript overlap: 40 nt Explain types of evidence for RNAi inhibition
External "C47D12.6" Links  Wormbase NCBI
[cgc5655]:tph-1:C47D12.7 Phenotypes Help with Phenotypes
Phenotype  Unclassified lipid metabolism abnormal
[cgc5655]:tph-1:C47D12.7 Experiment Details Ace View
Laboratory  GR
RNAi Reagent & Type  sjj_C47D12.7 (PCR_reagent)
Strain  tph-1(mg280)
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
Delivery Method  Bacterial_feeding
Date  2003-1-10
Gene Plot of C47D12.7 Browse using GBrowse
Gene Graph
Gene Plot of C47D12.6 Browse using GBrowse
Gene Graph