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RNAi Experiment: Cenix:10-e7 Ace View of Cenix:10-e7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZC168.4 (cyb-1)
Description of "ZC168.4"  cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage.
KOG Annotation  Cyclin B and related kinase-activating proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:10735641..10736289)
Transcript overlap: 570 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 507
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "ZC168.4" Links  Wormbase NCBI Phenobank 1
Cenix:10-e7 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Chromosome Segregation (karyomeres) abnormal
External Movies 
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Cenix:10-e7 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:10-e7 (PCR_reagent)
Remark  early embryonic: Chromosome Segregation (karyomeres)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of ZC168.4 Browse using GBrowse
Gene Graph