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RNAi Experiment: Cenix:102-c1 Ace View of Cenix:102-c1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y54E2A.3 (tac-1)
Description of "Y54E2A.3"  tac-1 encodes a novel protein that is a member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; TAC-1 is required during early embryogenesis for pronuclear migration and maintenance of microtubule stability and later, may also play roles in locomotion and establishment of normal body morphology; TAC-1 mutually stabilizes, and interacts in vivo with, ZYG-9, a microtubule-associated protein (MAP) that is also required for pronuclear migration; in vitro, TAC-1 interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 localizes primarily to spindle poles during mitosis.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:14753000..14753865)
Transcript overlap: 658 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 595
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y54E2A.3" Links  Wormbase NCBI Phenobank 1
Cenix:102-c1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Pnm
External Movies 
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Cenix:102-c1 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:102-c1 (PCR_reagent)
Remark  early embryonic: Pronuclear Migration
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y54E2A.3 Browse using GBrowse
Gene Graph