Ace View of Cenix:122-e2 | |||
Gene Inhibited | F26D10.3 (hsp-1) | ||
Description of "F26D10.3" | hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. | ||
KOG Annotation  | Molecular chaperones HSP70/HSC70, HSP70 superfamily |
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Evidence for Inhibition | |||
External "F26D10.3" Links | 1 | ||
Adult | Sterile F0/Fertility Problems Sterility/Impaired Fertility in F0 |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:122-e2 (PCR_reagent) | ||
Remark | early embryonic: Sterility/Impaired Fertility in F0 | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of F26D10.3 | |||