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RNAi Experiment: Cenix:122-e2 Ace View of Cenix:122-e2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F26D10.3 (hsp-1)
Description of "F26D10.3"  hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity.
KOG Annotation  Molecular chaperones HSP70/HSC70, HSP70 superfamily
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:17280686..17281198)
Transcript overlap: 459 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 417
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F26D10.3" Links  Wormbase NCBI Phenobank 1
Cenix:122-e2 Phenotypes Help with Phenotypes
Adult  Sterile F0/Fertility Problems
Sterility/Impaired Fertility in F0
Cenix:122-e2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:122-e2 (PCR_reagent)
Remark  early embryonic: Sterility/Impaired Fertility in F0
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F26D10.3 Browse using GBrowse
Gene Graph