Link to F42G8.5Link to F42G8.4.2Link to F42G8.4.1RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to F42G8.5Link to F42G8.4.2Link to F42G8.4.1Link to F42G8.3bLink to F42G8.3aRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Cenix:124-a6 Ace View of Cenix:124-a6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F42G8.5
Evidence for Inhibition 
ePCR Status: Best_ePCR (IV:8138424..8139692)
Transcript overlap: 589 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 505
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.857
Wormbase (BLAST) RNAi primary
External "F42G8.5" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  F42G8.4 (pmk-3)
Description of "F42G8.4"  pmk-3 encodes a homolog of p38, a mitogen-activated protein kinase (MAPK), activated in vitro by MEK6, indicating that it does respond like p38 to physiological stress; PMK-3 is expressed in nuclei throughout the intestine; PMK-3 is activated by osmotic stresses when heterologously expressed in mammalian cells; null mutants do not exhibit observable growth defects or hypersensitivity to several tested known stresses.
KOG Annotation  Mitogen-activated protein kinase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Bottom50_percentile_ePCR (IV:8138424..8139692)
Transcript overlap: 84 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 84
Relative score: 0.166 (Best raw score= for Gene )
Specificity index: 0.143
External "F42G8.4" Links  Wormbase NCBI Phenobank 1
Cenix:124-a6 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:124-a6 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:124-a6 (PCR_reagent)
Remark  3/3 tests are wildtype
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F42G8.5 Browse using GBrowse
Gene Graph
Gene Plot of F42G8.4 Browse using GBrowse
Gene Graph