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RNAi Experiment: Cenix:126-d9 Ace View of Cenix:126-d9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F58E6.10 (unc-42)
Description of "F58E6.10"  unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:9767007..9767706)
Transcript overlap: 383 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 320
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F58E6.10" Links  Wormbase NCBI Phenobank 1
Cenix:126-d9 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:126-d9 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:126-d9 (PCR_reagent)
Remark  3/3 tests are wt
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F58E6.10 Browse using GBrowse
Gene Graph