RNAi Experiment: Cenix:135-f4 |
Ace View of Cenix:135-f4
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Genes Inhibited |
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Gene Inhibited |
W02G9.1 (ndx-2) |
Description of "W02G9.1" |
ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways. |
KOG Annotation  |
Nucleoside diphosphate-sugar hydrolase of the MutT (NUDIX) family
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (V:2662838..2663194)
Transcript overlap: 250 nt |
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Sliding Window |
Raw score: 229
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "W02G9.1" Links |
1 |
Cenix:135-f4 Phenotypes |
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Phenotype |
WT
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Cenix:135-f4 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
Cenix:135-f4 (PCR_reagent) |
Remark |
3/3 wild type |
Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Delivery Method |
Injection |
Date |
2005-3-24 |
Gene Plot of W02G9.1 |
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