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RNAi Experiment: Cenix:135-f4 Ace View of Cenix:135-f4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  W02G9.1 (ndx-2)
Description of "W02G9.1"  ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
KOG Annotation  Nucleoside diphosphate-sugar hydrolase of the MutT (NUDIX) family
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:2662838..2663194)
Transcript overlap: 250 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 229
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "W02G9.1" Links  Wormbase NCBI Phenobank 1
Cenix:135-f4 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:135-f4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:135-f4 (PCR_reagent)
Remark  3/3 wild type
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of W02G9.1 Browse using GBrowse
Gene Graph