Ace View of Cenix:137-f8 | |||
Gene Inhibited | C23G10.4 (rpn-2) | ||
Description of "C23G10.4" | rpn-2 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory paritcle (RP) base subcomplex; RPN-2 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation; RPN-2 is expressed sporadically at all stages of development in the pharynx, intestine, body wall muscle, somatic gonad, neurons, and hypodermis. | ||
KOG Annotation  | 26S proteasome regulatory complex, subunit RPN2/PSMD1 |
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Evidence for Inhibition | |||
External "C23G10.4" Links | 1 2 | ||
Embryonic | Emb Penetrance None reported | ||
Phenotype | Passage Through Meiosis defective |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:137-f8 (PCR_reagent) | ||
Remark | early embryonic: Passage Through Meiosis | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of C23G10.4 | |||