| RNAi Experiment: Cenix:138-d8 |
Ace View of Cenix:138-d8
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| Genes Inhibited |
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| Gene Inhibited |
F14B8.1 (nhx-4) |
| Description of "F14B8.1" |
nhx-4 encodes two isoforms of a sodium/proton exchanger expressed in the plasma membrane of nearly all cells and cell types; in polarized epithelial cells, NHX-4::GFP appears specifically located in the basolateral membrane, like human SLC9A1 ('NHE1'; OMIM:107310); nhx-4 has no reported mutant or RNAi phenotype, but, given its ubiquitous expression, may represent a housekeeping exchanger generally required for cellular viability; transgenic NHX-4A, when expressed in cell culture, mediates Na[+]-dependent pH recovery after intracellular acidification, independently of extracellular Cl[-]. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (X:6919215..6920413)
Transcript overlap: 687 nt |
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| Sliding Window |
Raw score: 582
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "F14B8.1" Links |
   1 2 |
| Cenix:138-d8 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
Complex Phenotype
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:138-d8 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:138-d8 (PCR_reagent) |
| Remark |
early embryonic: Complex Phenotype |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of F14B8.1 |
Browse using GBrowse
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