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RNAi Experiment: Cenix:139-g11 Ace View of Cenix:139-g11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F57B10.3
Description of "F57B10.3"  F57B10.3 encodes an experimentally confirmed cofactor-independent phosphoglycerate mutase that is essential for embryonic and larval viability, and for normal body morphology; paradoxically, F57B10.3 is also required for normally short livespan (in mass RNAi screens for Age phenotypes); F57B10.3 is expressed widely in larvae and adults, with highest expression in the nerve ring, intestine and body wall muscles; F57B10.3 probably functions in glycolytic and gluconeogenic metabolism.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:6571621..6572819)
Transcript overlap: 814 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 751
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F57B10.3" Links  Wormbase NCBI Phenobank 1 2
Cenix:139-g11 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:139-g11 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:139-g11 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F57B10.3 Browse using GBrowse
Gene Graph