| RNAi Experiment: Cenix:140-a1 |
Ace View of Cenix:140-a1
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| Genes Inhibited |
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| Gene Inhibited |
H04J21.3 (gip-1) |
| Description of "H04J21.3" |
gip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (III:2359930..2361037)
Transcript overlap: 622 nt |
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| Sliding Window |
Raw score: 580
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "H04J21.3" Links |
   1 2 |
| Cenix:140-a1 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
Spindle Assembly abnormal
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:140-a1 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:140-a1 (PCR_reagent) |
| Remark |
early embryonic: Spindle Assembly |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of H04J21.3 |
Browse using GBrowse
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