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RNAi Experiment: Cenix:141-b8 Ace View of Cenix:141-b8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T24D1.1 (sqv-5)
Description of "T24D1.1"  sqv-5 encodes a chondroitin synthase that both initiates and elongates chondroitin chains (unlike human chondroitin synthase, which only elongates them); SQV-5 is required for cytokinesis (e.g., at the one-cell embryo stage), gonad migration, and vulval morphogenesis (by expanding the extracellular space of the vulva in L4 larvae); the common requirement for SQV-5 in both processes may be to promote filling an extracellular space with fluid (either in the eggshell, or underneath the L4 cuticle); SQV-5 colocalizes with SQV-1 at punctate foci (probably the Golgi apparatus) in the cytoplasm of the vulva, the uterus and oocytes; SQV-5 is most similar to human chondroitin synthase (KIAA0990) and Drosophila CG9220.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9949114..9950310)
Transcript overlap: 757 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 716
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T24D1.1" Links  Wormbase NCBI Phenobank 1
Cenix:141-b8 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:141-b8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:141-b8 (PCR_reagent)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T24D1.1 Browse using GBrowse
Gene Graph