| RNAi Experiment: Cenix:143-a10 |
Ace View of Cenix:143-a10
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| Genes Inhibited |
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| Gene Inhibited |
Y24D9A.4 (rpl-7A) |
| Description of "Y24D9A.4" |
rpl-8 encodes a large ribosomal subunit L7a protein required in mass RNAi assays for fertility, vulval development, and general health; the rpl-8 transcription unit has one nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-8 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-10, rpl-12) have protein products that are involved in translation. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (IV:4388994..4390180)
Transcript overlap: 712 nt |
|
| Sliding Window |
Raw score: 629
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.674 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "Y24D9A.4" Links |
   1 2 3 |
| Gene Inhibited |
Y24D9A.8 |
| Description of "Y24D9A.8" |
Y24D9A.8 is orthologous to the human gene TRANSALDOLASE 1 (TALDO1; OMIM:602063), which when mutated leads to disease. |
| Evidence for Inhibition |
| ePCR |
Transcript overlap: 6 nt |
|
|
| External "Y24D9A.8" Links |
1 2 3 |
| Gene Inhibited |
Y73B3A.18 |
| Description of "Y73B3A.18" |
Associated GO Term : structural constituent of ribosome |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 430
Relative score: 0.483 (Best raw score= for Gene )
Specificity index: 0.326 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "Y73B3A.18" Links |
1 2 3 |
| Cenix:143-a10 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
Severe Pleiotropic Defects
|
External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:143-a10 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:143-a10 (PCR_reagent) |
| Remark |
early embryonic: Severe Pleiotropic Defects |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of Y24D9A.4 |
Browse using GBrowse
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| Gene Plot of Y73B3A.18 |
Browse using GBrowse
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| Gene Plot of Y24D9A.8 |
Browse using GBrowse
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