Link to Y24D9A.2RNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentLink to Y73B3A.18aLink to Y73B3A.18bLink to Y108F1.3geneMap Link to Y24D9A.8a.1Link to Y24D9A.8b.1Link to Y24D9A.8a.2Link to Y24D9A.8b.2Link to Y24D9A.8a.3Link to Y24D9A.4a.1Link to Y24D9A.4a.2Link to Y24D9A.4cLink to Y24D9A.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to Y73B3A.18aLink to Y73B3A.18bLink to Y108F1.3geneMap Link to Y108F1.3RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentLink to Y24D9A.2geneMap
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RNAi Experiment: Cenix:143-g9 Ace View of Cenix:143-g9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y24D9A.2
Description of "Y24D9A.2"  Y24D9A.2 encodes a histone H3 (Lys9) methyltransferase ortholog, predicted to function in transcriptional repression; Y24D9A.2 protein is specifically cleaved by CED-3, both in a genomic expression screen and in an in vitro assay.
KOG Annotation  Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing
What's a KOG?
Evidence for Inhibition 
ePCR Status: Best_ePCR (IV:4390726..4391885)
Transcript overlap: 865 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 430
Relative score: 0.747 (Best raw score= for Gene )
Specificity index: 0.427
Wormbase (BLAST) RNAi secondary
External "Y24D9A.2" Links  Wormbase NCBI Phenobank 1 2
Gene Inhibited  Y24D9A.4 (rpl-7A)
Description of "Y24D9A.4"  rpl-8 encodes a large ribosomal subunit L7a protein required in mass RNAi assays for fertility, vulval development, and general health; the rpl-8 transcription unit has one nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-8 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-10, rpl-12) have protein products that are involved in translation.
Evidence for Inhibition 
ePCR Transcript overlap: 9 nt Explain types of evidence for RNAi inhibition
External "Y24D9A.4" Links  Wormbase NCBI Phenobank 1 2
Gene Inhibited  Y108F1.3
Evidence for Inhibition 
ePCR Status: Top50_percentile_ePCR (X:257194..258361)
Transcript overlap: 639 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 576
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.573
Wormbase (BLAST) RNAi primary
External "Y108F1.3" Links  Wormbase NCBI Phenobank 1 2
Cenix:143-g9 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:143-g9 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:143-g9 (PCR_reagent)
Remark  Wildtype results in all three tests.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y24D9A.4 Browse using GBrowse
Gene Graph
Gene Plot of Y108F1.3 Browse using GBrowse
Gene Graph
Gene Plot of Y24D9A.2 Browse using GBrowse
Gene Graph