Ace View of Cenix:145-c8 | |||
Gene Inhibited | B0334.11 (ooc-3) | ||
Description of "B0334.11" | ooc-3 encodes a nematode-specific protein with a predicted signal sequence, four predicted transmembrane domains, and two putative PEST sequences; OOC-3 is probably localized to the endoplasmic reticulum (ER), and is maternally required for correct localization of PAR-2 and PAR-3 in the P1 blastomere of the two-cell stage embryo; specifically, OOC-3 is required for restricting PAR-3 to the anterior cortex of the P1 blastomere to assure PAR-2 localization at the posterior cortex; more generally, OOC-3 is required to establish asymmetrical anterior-posterior cortical domains and spindle orientation in P1. | ||
Evidence for Inhibition | |||
External "B0334.11" Links | 1 2 | ||
Embryonic | Emb Penetrance None reported | ||
Phenotype | Complex Phenotype |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:145-c8 (PCR_reagent) | ||
Remark | early embryonic: Complex Phenotype | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of B0334.11 | |||