Link to C25A11.4aLink to C25A11.4bLink to C25A11.4dLink to C25A11.4cRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Cenix:146-f2 Ace View of Cenix:146-f2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C25A11.4 (ajm-1)
Description of "C25A11.4"  ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:9109702..9110901)
Transcript overlap: 854 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 770
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C25A11.4" Links  Wormbase NCBI Phenobank 1 2 3
Cenix:146-f2 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:146-f2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:146-f2 (PCR_reagent)
Remark  3/3 tests with wildtype results.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of C25A11.4 Browse using GBrowse
Gene Graph