Ace View of Cenix:148-e8 | |||
Gene Inhibited | F59E12.2 (zyg-1) | ||
Description of "F59E12.2" | zyg-1 encodes a homolog of polo-like and calcium-dependent kinases that is required for daughter centriole formation; ZYG-1 localizes transiently to centrosomes and acts at least one cell cycle prior to each spindle assembly event; ZYG-1 activity is required for proper localization of the SAS-5 and SAS-6 coiled-coil proteins that are also required for centriole duplication. | ||
KOG Annotation  | Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily |
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Evidence for Inhibition | |||
External "F59E12.2" Links | 1 | ||
Embryonic | Emb Penetrance None reported | ||
Phenotype | Spindle Assembly abnormal |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:148-e8 (PCR_reagent) | ||
Remark | early embryonic: Spindle Assembly | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of F59E12.2 | |||