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RNAi Experiment: Cenix:149-d4 Ace View of Cenix:149-d4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R06C7.7 (lin-61)
Description of "R06C7.7"  lin-61 encodes a protein that contains mbt repeats and has similarity to the Drosophila Polycomb group protein Sex Comb on Midleg and human protein H-l-(3)mbl-like; by homology, LIN-61 is predicted to function as part of a transcriptional regulatory complex that may play a role in transcriptional repression during development; loss of lin-61 activity via RNAi and forward mutations indicates that LIN-61 is required for: 1) genome stability in the soma and germline, and 2) postembryonic developmental processes such as vulval development, in which lin-61 acts as a class B synthetic multivulval (SynMuv) gene.
KOG Annotation  Polycomb group protein SCM/L(3)MBT (tumor-supressor in Drosophila and humans)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:7248902..7250101)
Transcript overlap: 1059 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 996
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R06C7.7" Links  Wormbase NCBI Phenobank 1
Cenix:149-d4 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:149-d4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:149-d4 (PCR_reagent)
Remark  Wildtype results for all three tests.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of R06C7.7 Browse using GBrowse
Gene Graph