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RNAi Experiment: Cenix:149-f3 Ace View of Cenix:149-f3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R05D11.5
KOG Annotation  Predicted membrane protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Best_ePCR (I:8591874..8592962)
Transcript overlap: 635 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 551
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.89
Wormbase (BLAST) RNAi primary
External "R05D11.5" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  R05D11.3 (ran-4)
Description of "R05D11.3"  ran-4 encodes a ortholog of NUCLEAR TRANSPORT FACTOR 2 (NTF2) from S. cerevisiae and metazoa, which is predicted to interact with nucleoporins and to promote transport of RAN-1(+GDP) into the nucleus; RAN-4/NTF2 proteins are paralogous to the N-terminal domain of RasGAP SH3 binding proteins such as Drosophila RASPUTIN, and to delta-5-3-ketosteroid isomerases, while having no homology to Ran proteins per se; RAN-4 is essential for early embryogenesis; in mass RNAi assays, ran-4 is needed for embryonic viability, normally rapid growth, fertility, and normal pronuclear envelopes in the embryo.
KOG Annotation  Nuclear transport factor 2
What's a KOG?
Evidence for Inhibition 
ePCR Status: Bottom50_percentile_ePCR (I:8591874..8592962)
Transcript overlap: 89 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 68
Relative score: 0.123 (Best raw score= for Gene )
Specificity index: 0.11
External "R05D11.3" Links  Wormbase NCBI Phenobank 1
Cenix:149-f3 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:149-f3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:149-f3 (PCR_reagent)
Remark  Wildtype results in all three tests.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of R05D11.3 Browse using GBrowse
Gene Graph
Gene Plot of R05D11.5 Browse using GBrowse
Gene Graph