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RNAi Experiment: Cenix:150-h7 Ace View of Cenix:150-h7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T22C8.8 (vab-9)
Description of "T22C8.8"  vab-9 encodes a claudin homolog orthologous to human brain cell membrane protein 1 (BCMP1) and Drosophila CG6982; VAB-9 colocalizes with HMP-1 to an apical layer of the adherens junctions of all epithelial cells, one layer more apically than AJM-1; vab-9 mutants have disorganized F-actin at the adherens junction, implying that VAB-9 links junctions to circumferential actin filaments; VAB-9 is also expressed in the nerve ring; VAB-9 requires the cadherin HMR-1 to localize to the cell membrane, and both alpha-catenin (HMP-1) and beta-catenin (HMP-2) to remain at the cell junction after membrane localization.
KOG Annotation  Brain cell membrane protein 1 (BCMP1)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:8636072..8637570)
Transcript overlap: 865 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 781
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T22C8.8" Links  Wormbase NCBI Phenobank 1
Cenix:150-h7 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:150-h7 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:150-h7 (PCR_reagent)
Remark  Wildtype results in all three tests.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T22C8.8 Browse using GBrowse
Gene Graph