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RNAi Experiment: Cenix:151-f7 Ace View of Cenix:151-f7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y38A8.2 (pbs-3)
Description of "Y38A8.2"  pbs-3 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-3 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-3 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-3 is required for embryonic and germline development, movement, normal body coloration, and normal body morphology.
KOG Annotation  20S proteasome, regulatory subunit beta type PSMB3/PUP3
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:4954891..4955665)
Transcript overlap: 474 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 432
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y38A8.2" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  Y38A8.3 (ulp-2)
Description of "Y38A8.3"  Associated GO Term : cysteine-type peptidase activity
KOG Annotation  Protease, Ulp1 family
What's a KOG?
Evidence for Inhibition 
ePCR Transcript overlap: 34 nt Explain types of evidence for RNAi inhibition
External "Y38A8.3" Links  Wormbase NCBI Phenobank 1
Cenix:151-f7 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Passage Through Meiosis defective
External Movies 
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Cenix:151-f7 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:151-f7 (PCR_reagent)
Remark  early embryonic: Passage Through Meiosis
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y38A8.3 Browse using GBrowse
Gene Graph
Gene Plot of Y38A8.2 Browse using GBrowse
Gene Graph