| RNAi Experiment: Cenix:152-a8 |
Ace View of Cenix:152-a8
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| Genes Inhibited |
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| Gene Inhibited |
Y48G1A.5 (imb-5) |
| Description of "Y48G1A.5" |
imb-5 encodes an importin-beta-like protein orthologous to mammalian CAS proteins (cellular apoptosis susceptibility) and Saccharomyces cerevisiae CSE1 (chromosome segregation 1); IMB-5 is predicted to function in nuclear transport of proteins required for mitotic progression or apoptosis as well as in re-export of importin-alpha, a nuclear import protein; in C. elegans, IMB-5 is essential for embryogenesis and required for normal pronuclear envelope dynamics, and may also play a role in vulval morphogenesis. |
| KOG Annotation |
Nuclear export receptor CSE1/CAS (importin beta superfamily)
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (I:322762..323400)
Transcript overlap: 519 nt |
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| Sliding Window |
Raw score: 477
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "Y48G1A.5" Links |
   1 |
| Cenix:152-a8 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
Pronuclear/Nuclear Appearance abnormal
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:152-a8 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:152-a8 (PCR_reagent) |
| Remark |
early embryonic: Pronuclear/Nuclear Appearance |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of Y48G1A.5 |
Browse using GBrowse
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