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RNAi Experiment: Cenix:155-e10 Ace View of Cenix:155-e10
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T28F12.2 (unc-62)
Description of "T28F12.2"  unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:4500587..4502043)
Transcript overlap: 445 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 383
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T28F12.2" Links  Wormbase NCBI Phenobank 1 2 3 4
Cenix:155-e10 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:155-e10 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:155-e10 (PCR_reagent)
Remark  early embryonic: Overall wildtype.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T28F12.2 Browse using GBrowse
Gene Graph