Ace View of Cenix:155-e10 | |||
Gene Inhibited | T28F12.2 (unc-62) | ||
Description of "T28F12.2" | unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles. | ||
Evidence for Inhibition | |||
External "T28F12.2" Links | 1 2 3 4 | ||
Embryonic | Emb Penetrance None reported | ||
Phenotype | WT_postembryonic_morphology |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:155-e10 (PCR_reagent) | ||
Remark | early embryonic: Overall wildtype. | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of T28F12.2 | |||