Link to C43E11.7RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: Cenix:159-e1 Ace View of Cenix:159-e1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C43E11.7 (ndx-7)
Description of "C43E11.7"  ndx-7 encodes a NUDIX hydrolase; by sequence comparison, NDX-7 is predicted to function as a pyrophosphatase, and is most closely related to the mouse RP2 protein that has unknown substrate specificity but is regulated transcriptionally by the presence of androgens; in C. elegans, loss of ndx-7 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
KOG Annotation  Predicted hydrolase RP2 (NUDIX/MutT superfamily)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:4241220..4242800)
Transcript overlap: 691 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 607
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C43E11.7" Links  Wormbase NCBI Phenobank 1
Cenix:159-e1 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:159-e1 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:159-e1 (PCR_reagent)
Remark  Wildtype result in all three tests.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of C43E11.7 Browse using GBrowse
Gene Graph