Link to F11C3.3.1Link to F32A7.7RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F32A7.6geneMap Link to F11C3.3.1Link to F32A7.7Link to F11C3.3.3Link to F11C3.3.4Link to F11C3.3.2Link to F11C3.3.5RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F32A7.6Link to F11C3.3.1Link to R06C7.10.1Link to R06C7.10.2geneMap Link to F32A7.5bLink to F32A7.5aLink to F32A7.5cLink to F32A7.6Link to F32A7.7RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F32A7.6Link to F11C3.3.1geneMap
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RNAi Experiment: Cenix:161-g6 Ace View of Cenix:161-g6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F32A7.7 (str-245)
Description of "F32A7.7"  Associated GO Term : G-protein coupled receptor activity
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:14852506..14853346)
Transcript overlap: 430 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 325
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F32A7.7" Links  Wormbase NCBI Phenobank 1 2
Gene Inhibited  F11C3.3 (unc-54)
Description of "F11C3.3"  unc-54 encodes a muscle myosin class II heavy chain (MHC B); UNC-54 is the major myosin heavy chain expressed in C. elegans and is required for locomotion and egg-laying; in vivo and in vitro, UNC-54 interacts with ITR-1, an IP3 receptor, and this interaction may provide a link between calcium signaling and the muscle cytoskeleton; UNC-54 is a thick filament component that is expressed in multiple muscle cell classes including body wall, intestinal, anal depressor, and sphincter muscles as well as sex-specific muscles that develop postembryonically.
KOG Annotation  Myosin class II heavy chain
What's a KOG?
Evidence for Inhibition 
ePCR Transcript overlap: 32 nt Explain types of evidence for RNAi inhibition
External "F11C3.3" Links  Wormbase NCBI Phenobank 1 2
Gene Inhibited  F32A7.6 (aex-5)
Description of "F32A7.6"  an ortholog of calcium-dependent serine endoproteinases, the kex2/subtilisin-like proprotein convertase that affects defecation cycle and anterior body contractions; and is expressed in all muscle cells except pharyngeal muscles.
KOG Annotation  Subtilisin-like proprotein convertase
What's a KOG?
Evidence for Inhibition 
ePCR Transcript overlap: 32 nt Explain types of evidence for RNAi inhibition
Wormbase (BLAST) RNAi primary
External "F32A7.6" Links  Wormbase NCBI Phenobank 1 2
Cenix:161-g6 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:161-g6 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:161-g6 (PCR_reagent)
Remark  Overall wildtype.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F32A7.7 Browse using GBrowse
Gene Graph
Gene Plot of F32A7.6 Browse using GBrowse
Gene Graph
Gene Plot of F11C3.3 Browse using GBrowse
Gene Graph