RNAi Experiment: Cenix:161-h2 |
Ace View of Cenix:161-h2
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Genes Inhibited |
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Gene Inhibited |
F26H9.7 (uev-3) |
Description of "F26H9.7" |
uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage. |
KOG Annotation  |
Ubiquitin-protein ligase
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:9310972..9312455)
Transcript overlap: 521 nt |
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Sliding Window |
Raw score: 437
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F26H9.7" Links |
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Cenix:161-h2 Phenotypes |
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Phenotype |
WT
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Cenix:161-h2 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
Cenix:161-h2 (PCR_reagent) |
Remark |
Wildtype results for all three tests. |
Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Delivery Method |
Injection |
Date |
2005-3-24 |
Gene Plot of F26H9.7 |
Browse using GBrowse
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