Ace View of Cenix:168-d6 | |||||||
Gene Inhibited | Y38C1AB.4 | ||||||
Description of "Y38C1AB.4" | Associated GO Term : cytoskeleton | ||||||
KOG Annotation  | Membrane-associated protein tyrosine phosphatase PTP-BAS and related proteins, contain FERM domain |
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Evidence for Inhibition |
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External "Y38C1AB.4" Links | 1 2 | ||||||
Gene Inhibited | Y38C1AB.8 (frm-5) | ||||||
Description of "Y38C1AB.8" | frm-5 encodes a protein that contains a FERM (Band 4.1-ezrin-radixin-moesin) domain near the center of the molecule and two C-terminal PDZ domains; by homology, FRM-5 is predicted to function as a membrane-cytoskeleton linker protein that plays a role in cell adhesion, migration, or organization of cell surface structures; however, as loss of frm-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of FRM-5 in C. elegans development and/or behavior is not yet known; the FRM-5 FERM and PDZ domains are most similar to those found in cytoplasmic protein tyrosine phosphatases, even though FRM-5 does not appear to be a phosphatase. | ||||||
KOG Annotation  | Membrane-associated protein tyrosine phosphatase PTP-BAS and related proteins, contain FERM domain |
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Evidence for Inhibition | |||||||
External "Y38C1AB.8" Links | 1 2 | ||||||
Phenotype | WT |
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Laboratory | TH | ||||||
RNAi Reagent & Type | Cenix:168-d6 (PCR_reagent) | ||||||
Remark | Wildtype results in all three tests. | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
Delivery Method | Injection | ||||||
Date | 2005-3-24 | ||||||
Gene Plot of Y38C1AB.8 | |||||||
Gene Plot of Y38C1AB.4 | |||||||