Link to M18.5Link to M18.6RNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Cenix:18-e8 Ace View of Cenix:18-e8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  M18.5
Description of "M18.5"  M18.5 is orthologous to the human gene DAMAGE-SPECIFIC DNA BINDING PROTEIN 1 (127KD) (DDB1; OMIM:600045), which when mutated leads to disease.
KOG Annotation  Damage-specific DNA binding complex, subunit DDB1
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:12118485..12119048)
Transcript overlap: 516 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 474
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "M18.5" Links  Wormbase NCBI Phenobank 1
Cenix:18-e8 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
(Please note that RNAiDB is not
hosting these data.)
/static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Help
Cenix:18-e8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:18-e8 (PCR_reagent)
Remark  40-60% of embryonic lethality. Escapers arrest/die at larval stage or develop into sterile adults with protruding vulvae.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of M18.5 Browse using GBrowse
Gene Graph