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RNAi Experiment: Cenix:18-h3 Ace View of Cenix:18-h3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F07A5.7 (unc-15)
Description of "F07A5.7"  The unc-15 gene encodes a paramyosin ortholog; UNC-15 protein physically interacts with MHC A, one isoform of myosin heavy chain (MHC) in striated muscle; UNC-15 accumulation is decreased in the absence of UNC-54 (myosin B), implying that degradation of UNC-15 is inhibited by its binding myosin B; conversely, myosin B (but not MYO-3/myosin A) fails to accumulate in unc-15 mutants.
KOG Annotation  Myosin class II heavy chain
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:7379015..7379595)
Transcript overlap: 514 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 493
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F07A5.7" Links  Wormbase NCBI Phenobank 1
Cenix:18-h3 Phenotypes Help with Phenotypes
Phenotype  Larval Lethal-Late (L3/L4)
External Movies 
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Cenix:18-h3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:18-h3 (PCR_reagent)
Remark  early embryonic: Two independent experiments, one of which showed a non-reproducible polar body extrusion defect.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F07A5.7 Browse using GBrowse
Gene Graph