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RNAi Experiment: Cenix:189-h3 Ace View of Cenix:189-h3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y39G10AL.3 (cdk-7)
Description of "Y39G10AL.3"  The cdk-7 gene encodes a cyclin-dependent kinase orthologous to human CDK7 (OMIM:601955) that is a component of the general transcription factor IIH (TFIIH) complex; CDK-7 is required during embryogenesis for mRNA transcription and phosphorylation of RNA polymerase II on serine 2 and serine 5, as well as for cell cycle progression, maintenance of ploidy, and completion of meiosis following fertilization.
KOG Annotation  Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:2287602..2287740)
Transcript overlap: 139 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 118
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y39G10AL.3" Links  Wormbase NCBI Phenobank 1
Cenix:189-h3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:189-h3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:189-h3 (PCR_reagent)
Remark  early embryonic: Clear-cut result.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y39G10AL.3 Browse using GBrowse
Gene Graph