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RNAi Experiment: Cenix:19-c11 Ace View of Cenix:19-c11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F11C3.3 (unc-54)
Description of "F11C3.3"  unc-54 encodes a muscle myosin class II heavy chain (MHC B); UNC-54 is the major myosin heavy chain expressed in C. elegans and is required for locomotion and egg-laying; in vivo and in vitro, UNC-54 interacts with ITR-1, an IP3 receptor, and this interaction may provide a link between calcium signaling and the muscle cytoskeleton; UNC-54 is a thick filament component that is expressed in multiple muscle cell classes including body wall, intestinal, anal depressor, and sphincter muscles as well as sex-specific muscles that develop postembryonically.
KOG Annotation  Myosin class II heavy chain
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:14856101..14856772)
Transcript overlap: 572 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 509
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F11C3.3" Links  Wormbase NCBI Phenobank 1
Cenix:19-c11 Phenotypes Help with Phenotypes
Phenotype  WT
External Movies 
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hosting these data.)
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Cenix:19-c11 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:19-c11 (PCR_reagent)
Remark  early embryonic: Only low reproducible defects found in two other experiments.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F11C3.3 Browse using GBrowse
Gene Graph