| RNAi Experiment: Cenix:199-b7 |
Ace View of Cenix:199-b7
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| Genes Inhibited |
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| Gene Inhibited |
R119.6 (taf-4) |
| Description of "R119.6" |
taf-4 encodes a TAFII (TBP(TATA-binding protein)-associated factor) that is orthologous to human TAF4 (hTAFII130); TAF-4 is predicted to be a component of the TFIID mRNA transcription complex and is generally required for early embryonic mRNA transcription; consistent with this observation, taf-4(RNAi) results in embryonic lethality at the ~100-cell stage with little cell differentiation, similar to the loss of AMA-1/RNA polymerase II activity; TAF-4 is detected in nuclei in the adult germline, oocytes, and embryo, from the 2-cell stage through early morphogenesis. |
| KOG Annotation |
TATA box binding protein (TBP)-associated factor, RNA polymerase II
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (I:383419..383568)
Transcript overlap: 136 nt |
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| Sliding Window |
Raw score: 116
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "R119.6" Links |
   1 |
| Cenix:199-b7 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
WT_postembryonic_morphology
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:199-b7 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:199-b7 (PCR_reagent) |
| Remark |
early embryonic: Clear cut result. |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of R119.6 |
Browse using GBrowse
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