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RNAi Experiment: Cenix:20-b4 Ace View of Cenix:20-b4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F55C5.5
Description of "F55C5.5"  F55C5.5 encodes a translational elongation factor Ts (EF-Ts) that binds two different EF-Tu proteins (EF-TU1/Y71H2AM.23 and EF-TU2/C43E11.4) in vitro, stimulating guanine-nucleotide exchange and mRNA translation; F55C5.5 is predicted to be mitochondrial and has a putative N-terminal transit peptide sequence; F55C5.5 is required in mass RNAi assays for normally rapid growth and for maintenance of the germline.
KOG Annotation  Mitochondrial translation elongation factor EF-Tsmt, catalyzes nucleotide exchange on EF-Tumt
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:12273369..12273999)
Transcript overlap: 547 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 486
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F55C5.5" Links  Wormbase NCBI Phenobank 1
Cenix:20-b4 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:20-b4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:20-b4 (PCR_reagent)
Remark  Medium penetrance embryonic lethality, escapers partly show a developmental delay or arrest at larval stage.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F55C5.5 Browse using GBrowse
Gene Graph