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RNAi Experiment: Cenix:20-b7 Ace View of Cenix:20-b7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R06C7.10 (let-75)
Description of "R06C7.10"  let-75 encodes a pharynx-specific type II myosin heavy chain (MHC D); LET-75 is required for pharyngeal muscle contraction and thus for normal feeding behavior and post-embryonic development; in vitro, the LET-75 tail domain interacts with ITR-1, an IP3 receptor, and this interaction has been proposed to mediate, in vivo, increased pharnygeal pumping in response to food; LET-75 is expressed exclusively in pharyngeal muscle.
KOG Annotation  Myosin class II heavy chain
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:7264785..7265437)
Transcript overlap: 502 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 313
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R06C7.10" Links  Wormbase NCBI Phenobank 1
Cenix:20-b7 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:20-b7 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:20-b7 (PCR_reagent)
Remark  early embryonic: Clear cut result.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of R06C7.10 Browse using GBrowse
Gene Graph