Link to T05H10.5cLink to T05H10.5aLink to T05H10.5bLink to T05H10.6a.3Link to T05H10.6b.2Link to T05H10.6b.1Link to T05H10.6a.4Link to T05H10.6a.2Link to T05H10.6a.1RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to T05H10.5cLink to T05H10.6b.2Link to T05H10.6b.1Link to T05H10.6a.3Link to T05H10.6a.4Link to T05H10.6a.1Link to T05H10.6a.2geneMap Link to T05H10.5cLink to T05H10.5bLink to T05H10.5aLink to T05H10.6a.3Link to T05H10.6b.2Link to T05H10.6b.1Link to T05H10.6a.1Link to T05H10.6a.2Link to T05H10.6a.4RNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to T05H10.5cLink to T05H10.6b.2Link to T05H10.6b.1Link to T05H10.6a.3Link to T05H10.6a.4Link to T05H10.6a.1Link to T05H10.6a.2geneMap
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RNAi Experiment: Cenix:20-f8 Ace View of Cenix:20-f8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T05H10.5 (ufd-2)
Description of "T05H10.5"  Associated GO Term : ubiquitin-protein ligase activity
Evidence for Inhibition 
ePCR Status: Best_ePCR (II:8066875..8067462)
Transcript overlap: 509 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 467
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.5
External "T05H10.5" Links  Wormbase NCBI Phenobank 1 2
Gene Inhibited  T05H10.6
Description of "T05H10.6"  T05H10.6 encodes an ortholog of the human gene PYRUVATE DEHYDROGENASE (LIPOAMIDE) ALPHA 1 (PDHA1; OMIM:312170), which when mutated leads to Leigh syndrome (OMIM:256000); the T05H10.6 protein is predicted to be mitochondrial with 68% accuracy.
KOG Annotation  Pyruvate dehydrogenase E1, alpha subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Best_ePCR (II:8066875..8067462)
Transcript overlap: 509 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 467
Specificity index: 0.5
Wormbase (BLAST) RNAi primary
External "T05H10.6" Links  Wormbase NCBI Phenobank 1 2
Cenix:20-f8 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
External Movies 
(Please note that RNAiDB is not
hosting these data.)
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Cenix:20-f8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:20-f8 (PCR_reagent)
Remark  early embryonic: All events are significantly slowed down.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T05H10.6 Browse using GBrowse
Gene Graph
Gene Plot of T05H10.5 Browse using GBrowse
Gene Graph