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RNAi Experiment: Cenix:20-g5 Ace View of Cenix:20-g5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  K07A12.3 (asg-1)
Description of "K07A12.3"  asg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology.
KOG Annotation  Mitochondrial F1F0-ATP synthase, subunit g/ATP20
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:8692864..8693519)
Transcript overlap: 477 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 435
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "K07A12.3" Links  Wormbase NCBI Phenobank 1 2
Gene Inhibited  K07A12.5
Evidence for Inhibition 
ePCR Transcript overlap: 35 nt Explain types of evidence for RNAi inhibition
Wormbase (BLAST) RNAi primary
External "K07A12.5" Links  Wormbase NCBI Phenobank 1 2
Cenix:20-g5 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
External Movies 
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Cenix:20-g5 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:20-g5 (PCR_reagent)
Remark  early embryonic: Significant drop in the overall sequence of events observed. Also meiotic arrest in one of the experiments. Worms cease to produce eggs.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of K07A12.3 Browse using GBrowse
Gene Graph
Gene Plot of K07A12.5 Browse using GBrowse
Gene Graph