Ace View of Cenix:20-g5 | |||||||
Gene Inhibited | K07A12.3 (asg-1) | ||||||
Description of "K07A12.3" | asg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology. | ||||||
KOG Annotation  | Mitochondrial F1F0-ATP synthase, subunit g/ATP20 |
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Evidence for Inhibition | |||||||
External "K07A12.3" Links | 1 2 | ||||||
Gene Inhibited | K07A12.5 | ||||||
Evidence for Inhibition |
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External "K07A12.5" Links | 1 2 | ||||||
Embryonic | Emb Penetrance None reported | ||||||
External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||||||
RNAi Reagent & Type | Cenix:20-g5 (PCR_reagent) | ||||||
Remark | early embryonic: Significant drop in the overall sequence of events observed. Also meiotic arrest in one of the experiments. Worms cease to produce eggs. | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
Delivery Method | Injection | ||||||
Date | 2005-3-24 | ||||||
Gene Plot of K07A12.3 | |||||||
Gene Plot of K07A12.5 | |||||||