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RNAi Experiment: Cenix:202-d2 Ace View of Cenix:202-d2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F52H3.1 (let-268)
Description of "F52H3.1"  let-268 encodes a procollagen lysyl hydroxylase that processes type IV collagen, a collagen secreted and incorporated into the basement membrane during embryogenesis (and encoded partly by emb-9); LET-268 activity is essential for type IV collagen processing and secretion and for the stability, but not the formation of, the basement membrane that provides mechanical support to body wall muscle once contraction begins; LET-268 also appears to be required for pharyngeal muscle contraction.
KOG Annotation  Lysyl hydroxylase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:10036636..10037784)
Transcript overlap: 875 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 854
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F52H3.1" Links  Wormbase NCBI Phenobank 1
Cenix:202-d2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:202-d2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:202-d2 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F52H3.1 Browse using GBrowse
Gene Graph