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RNAi Experiment: Cenix:204-c9 Ace View of Cenix:204-c9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  EGAP2.3 (pho-1)
Description of "EGAP2.3"  pho-1 encodes the major C. elegans intestinal acid phosphatase; as loss of PHO-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, PHO-1 may function redundantly with other acid phosphatases; PHO-1 intestinal expression appears to be positively regulated by CKI-1, a cyclin-dependent kinase inhibitor, and negatively regulated by POP-1, a TCF/LEF transcription factor; PHO-1 is expressed along the intestinal brush border in all gut cells except the most anterior int-1 and int-2 cells, beginning at the three-fold stage of embryogenesis.
KOG Annotation  Lysosomal & prostatic acid phosphatases
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:5233213..5234111)
Transcript overlap: 633 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 549
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "EGAP2.3" Links  Wormbase NCBI Phenobank 1
Cenix:204-c9 Phenotypes Help with Phenotypes
Phenotype  WT
External Movies 
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Cenix:204-c9 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:204-c9 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of EGAP2.3 Browse using GBrowse
Gene Graph