RNAi Experiment: Cenix:211-b4 |
Ace View of Cenix:211-b4
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Genes Inhibited |
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Gene Inhibited |
K05F1.7 (msp-63) |
Description of "K05F1.7" |
msp-63 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (II:5796940..5797678)
Transcript overlap: 384 nt |
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Sliding Window |
Raw score: 342
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.409 |
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External "K05F1.7" Links |
1 |
Gene Inhibited |
K05F1.2 (msp-142) |
Description of "K05F1.2" |
msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 155
Relative score: 0.453 (Best raw score= for Gene )
Specificity index: 0.185 |
Wormbase (BLAST) |
RNAi secondary |
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External "K05F1.2" Links |
1 |
Gene Inhibited |
ZK1248.4 |
Description of "ZK1248.4" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 90
Relative score: 0.263 (Best raw score= for Gene )
Specificity index: 0.108 |
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External "ZK1248.4" Links |
1 |
Gene Inhibited |
ZK1248.6 (msp-64) |
Description of "ZK1248.6" |
msp-64 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 149
Relative score: 0.436 (Best raw score= for Gene )
Specificity index: 0.178 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK1248.6" Links |
1 |
Gene Inhibited |
ZK1248.17 |
Description of "ZK1248.17" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 100
Relative score: 0.292 (Best raw score= for Gene )
Specificity index: 0.12 |
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External "ZK1248.17" Links |
1 |
Cenix:211-b4 Phenotypes |
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Phenotype |
WT
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Cenix:211-b4 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
Cenix:211-b4 (PCR_reagent) |
Remark |
early embryonic: No significant defects seen in any of the recordings. |
Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Delivery Method |
Injection |
Date |
2005-3-24 |
Gene Plot of K05F1.2 |
Browse using GBrowse
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Gene Plot of K05F1.7 |
Browse using GBrowse
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Gene Plot of ZK1248.4 |
Browse using GBrowse
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Gene Plot of ZK1248.17 |
Browse using GBrowse
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Gene Plot of ZK1248.6 |
Browse using GBrowse
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