RNAi Experiment: Cenix:211-g4 |
Ace View of Cenix:211-g4
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Genes Inhibited |
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Gene Inhibited |
R05F9.8 (msp-33) |
Description of "R05F9.8" |
msp-33 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-33 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (II:4892034..4892663)
Transcript overlap: 407 nt |
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Sliding Window |
Raw score: 365
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.123 |
Wormbase (BLAST) |
RNAi primary |
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External "R05F9.8" Links |
1 |
Gene Inhibited |
Y59E9AR.7 |
Description of "Y59E9AR.7" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 98
Specificity index: 0.033 |
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External "Y59E9AR.7" Links |
1 |
Gene Inhibited |
R05F9.3 (msp-32) |
Description of "R05F9.3" |
msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 146
Relative score: 0.4 (Best raw score= for Gene )
Specificity index: 0.049 |
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External "R05F9.3" Links |
1 |
Gene Inhibited |
C09B9.6 (msp-55) |
Description of "C09B9.6" |
msp-55 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 75
Relative score: 0.205 (Best raw score= for Gene )
Specificity index: 0.025 |
Wormbase (BLAST) |
RNAi secondary |
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External "C09B9.6" Links |
1 |
Gene Inhibited |
F36H12.7 (msp-19) |
Description of "F36H12.7" |
msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 142
Relative score: 0.389 (Best raw score= for Gene )
Specificity index: 0.048 |
Wormbase (BLAST) |
RNAi secondary |
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External "F36H12.7" Links |
1 |
Gene Inhibited |
Y59E9AR.1 |
Description of "Y59E9AR.1" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 98
Relative score: 0.268 (Best raw score= for Gene )
Specificity index: 0.033 |
Wormbase (BLAST) |
RNAi secondary |
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External "Y59E9AR.1" Links |
1 |
Gene Inhibited |
R13H9.2 (msp-57) |
Description of "R13H9.2" |
msp-57 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 96
Relative score: 0.263 (Best raw score= for Gene )
Specificity index: 0.032 |
Wormbase (BLAST) |
RNAi secondary |
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External "R13H9.2" Links |
1 |
Gene Inhibited |
ZK546.3 |
Description of "ZK546.3" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 179
Relative score: 0.49 (Best raw score= for Gene )
Specificity index: 0.06 |
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External "ZK546.3" Links |
1 |
Gene Inhibited |
ZK354.5 (msp-51) |
Description of "ZK354.5" |
msp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 90
Relative score: 0.247 (Best raw score= for Gene )
Specificity index: 0.03 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK354.5" Links |
1 |
Gene Inhibited |
ZK354.10 (msp-58) |
Description of "ZK354.10" |
msp-58 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 110
Relative score: 0.301 (Best raw score= for Gene )
Specificity index: 0.037 |
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External "ZK354.10" Links |
1 |
Gene Inhibited |
T13F2.10 (msp-79) |
Description of "T13F2.10" |
msp-79 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "T13F2.10" Links |
1 |
Gene Inhibited |
F32B6.6 (msp-77) |
Description of "F32B6.6" |
msp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "F32B6.6" Links |
1 |
Gene Inhibited |
F58A6.8 (msp-45) |
Description of "F58A6.8" |
msp-45 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 70
Specificity index: 0.024 |
Wormbase (BLAST) |
RNAi secondary |
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External "F58A6.8" Links |
1 |
Gene Inhibited |
C34F11.4 (msp-50) |
Description of "C34F11.4" |
msp-50 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 70
Specificity index: 0.024 |
Wormbase (BLAST) |
RNAi secondary |
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External "C34F11.4" Links |
1 |
Gene Inhibited |
C33F10.9 (msp-40) |
Description of "C33F10.9" |
msp-40 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 61
Relative score: 0.167 (Best raw score= for Gene )
Specificity index: 0.02 |
Wormbase (BLAST) |
RNAi secondary |
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External "C33F10.9" Links |
1 |
Gene Inhibited |
R13H9.4 (msp-53) |
Description of "R13H9.4" |
msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 123
Relative score: 0.337 (Best raw score= for Gene )
Specificity index: 0.041 |
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External "R13H9.4" Links |
1 |
Gene Inhibited |
ZK354.4 (msp-113) |
Description of "ZK354.4" |
msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 89
Relative score: 0.244 (Best raw score= for Gene )
Specificity index: 0.03 |
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External "ZK354.4" Links |
1 |
Gene Inhibited |
ZK354.11 (msp-59) |
Description of "ZK354.11" |
msp-59 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 95
Relative score: 0.26 (Best raw score= for Gene )
Specificity index: 0.032 |
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External "ZK354.11" Links |
1 |
Gene Inhibited |
C34F11.6 (msp-49) |
Description of "C34F11.6" |
msp-49 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 82
Relative score: 0.225 (Best raw score= for Gene )
Specificity index: 0.028 |
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External "C34F11.6" Links |
1 |
Gene Inhibited |
K05F1.2 (msp-142) |
Description of "K05F1.2" |
msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 70
Relative score: 0.192 (Best raw score= for Gene )
Specificity index: 0.024 |
Wormbase (BLAST) |
RNAi secondary |
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External "K05F1.2" Links |
1 |
Gene Inhibited |
F26G1.7 (msp-3) |
Description of "F26G1.7" |
msp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 88
Relative score: 0.241 (Best raw score= for Gene )
Specificity index: 0.03 |
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External "F26G1.7" Links |
1 |
Gene Inhibited |
ZK354.1 (msp-65) |
Description of "ZK354.1" |
msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 92
Relative score: 0.252 (Best raw score= for Gene )
Specificity index: 0.031 |
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External "ZK354.1" Links |
1 |
Gene Inhibited |
ZK546.6 (msp-152) |
Description of "ZK546.6" |
msp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 236
Relative score: 0.647 (Best raw score= for Gene )
Specificity index: 0.079 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK546.6" Links |
1 |
Gene Inhibited |
F58A6.9 |
Description of "F58A6.9" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 81
Relative score: 0.222 (Best raw score= for Gene )
Specificity index: 0.027 |
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External "F58A6.9" Links |
1 |
Gene Inhibited |
F26G1.8 (msp-42) |
Description of "F26G1.8" |
msp-42 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 72
Relative score: 0.197 (Best raw score= for Gene )
Specificity index: 0.024 |
Wormbase (BLAST) |
RNAi secondary |
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External "F26G1.8" Links |
1 |
Gene Inhibited |
F36H12.6 (msp-52) |
Description of "F36H12.6" |
msp-52 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 104
Relative score: 0.285 (Best raw score= for Gene )
Specificity index: 0.035 |
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External "F36H12.6" Links |
1 |
Gene Inhibited |
R05F9.13 (msp-31) |
Description of "R05F9.13" |
msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm. |
Evidence for Inhibition |
Sliding Window |
Raw score: 153
Relative score: 0.419 (Best raw score= for Gene )
Specificity index: 0.051 |
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External "R05F9.13" Links |
1 |
Gene Inhibited |
F59A6.8 (msp-71) |
Description of "F59A6.8" |
msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 93
Relative score: 0.255 (Best raw score= for Gene )
Specificity index: 0.031 |
Wormbase (BLAST) |
RNAi secondary |
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External "F59A6.8" Links |
1 |
Cenix:211-g4 Phenotypes |
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Phenotype |
WT
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Cenix:211-g4 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
Cenix:211-g4 (PCR_reagent) |
Remark |
Wildtype results in all three tests. |
Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Delivery Method |
Injection |
Date |
2005-3-24 |
Gene Plot of Y59E9AR.7 |
Browse using GBrowse
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Gene Plot of R05F9.3 |
Browse using GBrowse
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Gene Plot of C09B9.6 |
Browse using GBrowse
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Gene Plot of F36H12.7 |
Browse using GBrowse
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Gene Plot of Y59E9AR.1 |
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Gene Plot of R13H9.2 |
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Gene Plot of ZK546.3 |
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Gene Plot of F58A6.8 |
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Gene Plot of F32B6.6 |
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Gene Plot of T13F2.10 |
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Gene Plot of ZK354.10 |
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Gene Plot of ZK354.5 |
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Gene Plot of C33F10.9 |
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Gene Plot of C34F11.4 |
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Gene Plot of ZK354.4 |
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Gene Plot of R13H9.4 |
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Gene Plot of R05F9.8 |
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Gene Plot of C34F11.6 |
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Gene Plot of ZK354.11 |
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Gene Plot of K05F1.2 |
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Gene Plot of F26G1.7 |
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Gene Plot of F58A6.9 |
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Gene Plot of ZK546.6 |
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Gene Plot of ZK354.1 |
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Gene Plot of F26G1.8 |
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Gene Plot of F36H12.6 |
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Gene Plot of F59A6.8 |
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Gene Plot of R05F9.13 |
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