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RNAi Experiment: Cenix:214-d1 Ace View of Cenix:214-d1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y39A3CR.4 (ddp-1)
Description of "Y39A3CR.4"  ddp-1 encodes the C. elegans ortholog of Saccharomyces cerevisiae Tim8p and human deafness/dystonia peptide (DDP; OMIM:300356, mutated in Mohr-Tranebjaerg syndrome); by homology, DDP-1 is predicted to be part of a heterooligomeric complex that localizes to the mitochondrial intermembrane space and facilitates translocation of proteins from the cytosol to the inner mitochondrial membrane; loss of ddp-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, indicating that ddp-1 is not essential for C. elegans development or may function redundantly with its paralogs, TIN-9, -10, and -13.
KOG Annotation  Mitochondrial import inner membrane translocase, subunit TIM8
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:1859902..1860049)
Transcript overlap: 148 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 127
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y39A3CR.4" Links  Wormbase NCBI Phenobank 1
Cenix:214-d1 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:214-d1 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:214-d1 (PCR_reagent)
Remark  Wildtype results in all three tests.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y39A3CR.4 Browse using GBrowse
Gene Graph