| RNAi Experiment: Cenix:22-a6 |
Ace View of Cenix:22-a6
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| Genes Inhibited |
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| Gene Inhibited |
C15H9.6 (hsp-3) |
| Description of "C15H9.6" |
hsp-3 encodes a heat shock response 70 (hsp70) protein orthologous to human glucose regulated protein 78 (grp78/BiP, OMIM:138120); HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage; HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. |
| KOG Annotation |
Molecular chaperones GRP78/BiP/KAR2, HSP70 superfamily
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (X:6089342..6089930)
Transcript overlap: 586 nt |
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| Sliding Window |
Raw score: 547
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "C15H9.6" Links |
   1 |
| Cenix:22-a6 Phenotypes |
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| Phenotype |
WT
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:22-a6 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:22-a6 (PCR_reagent) |
| Remark |
early embryonic: Three independent experiments, two of which showed low reprocucible defects. |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of C15H9.6 |
Browse using GBrowse
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