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RNAi Experiment: Cenix:235-a12 Ace View of Cenix:235-a12
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y46H3A.3 (hsp-16.2)
Description of "Y46H3A.3"  hsp-16.2 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; hsp-16.2 expression, strongest in intestine and pharynx, is induced in response to heat shock or other environmental stresses; HSP-16.2 has been shown to interact with intracellular human beta amyloid peptide, a primary component of the extracellular plaques found in Alzheimer's disease; HSP-16.2 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating.
KOG Annotation  Alpha crystallins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:1804375..1804508)
Transcript overlap: 134 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 92
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y46H3A.3" Links  Wormbase NCBI Phenobank 1
Cenix:235-a12 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:235-a12 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:235-a12 (PCR_reagent)
Remark  Wildtype results in all three tests.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y46H3A.3 Browse using GBrowse
Gene Graph