| RNAi Experiment: Cenix:236-g6 |
Ace View of Cenix:236-g6
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| Genes Inhibited |
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| Gene Inhibited |
C34F11.4 (msp-50) |
| Description of "C34F11.4" |
msp-50 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (II:5199818..5199909)
Transcript overlap: 92 nt |
|
| Wormbase (BLAST) |
RNAi primary |
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| External "C34F11.4" Links |
   1 |
| Cenix:236-g6 Phenotypes |
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| Phenotype |
WT
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| Cenix:236-g6 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:236-g6 (PCR_reagent) |
| Remark |
Wildtype results in all three tests. |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of C34F11.4 |
Browse using GBrowse
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