RNAi Experiment: Cenix:242-a4 |
Ace View of Cenix:242-a4
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Genes Inhibited |
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Gene Inhibited |
F54A5.3 |
Description of "F54A5.3" |
F54A5.3 encodes four proteins by multiple splicing, three of which are rather small (52-81 residues); however, one isoform (F54A5.3A, 316 residues) is a ortholog of vertebrate Shc proteins (e.g., p52/p46SHC and p66SHC); like its orthologs, F54A5.3A has a PTB and an SH2 domain in N- to C-terminal order; F54A5.3 has no obvious function in mass RNAi assays, but might be involved in RAS signal transduction or regulation of apoptosis. |
KOG Annotation  |
Adaptor protein SHC and related proteins
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:971717..972092)
Transcript overlap: 372 nt |
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Sliding Window |
Raw score: 331
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F54A5.3" Links |
1 2 3 |
Cenix:242-a4 Phenotypes |
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Phenotype |
WT
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Cenix:242-a4 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
Cenix:242-a4 (PCR_reagent) |
Remark |
3/3 tests are wildtype |
Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Delivery Method |
Injection |
Date |
2005-3-24 |
Gene Plot of F54A5.3 |
Browse using GBrowse
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