Link to T28C6.5Link to T28C6.4RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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ReagentLink to F56B3.1Link to M18.1geneMap Link to B0222.8RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to W05B2.4Link to W05B2.6RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to F11G11.10RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Cenix:242-f8 Ace View of Cenix:242-f8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T28C6.4 (col-117)
Description of "T28C6.4"  Associated GO Term : structural constituent of cuticle
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:8822916..8823337)
Transcript overlap: 396 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 357
Relative score: 0.992 (Best raw score= for Gene )
Specificity index: 0.156
External "T28C6.4" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  T15B7.3 (col-143)
Description of "T15B7.3"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 360
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.157
External "T15B7.3" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  B0222.8 (col-10)
Description of "B0222.8"  col-10 encodes a collagen protein; expressed exclusively in hypodermal cells
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 240
Specificity index: 0.105
External "B0222.8" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  W05B2.6 (col-92)
Description of "W05B2.6"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 101
Specificity index: 0.044
External "W05B2.6" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  T28C6.6 (col-3)
Description of "T28C6.6"  col-3 encodes a collagen protein that affects body morphogenesis, larval viability, and locomotion in large scale RNAi screens; mRNA is expressed during all developmental stages examined (in embryos, during the L2 to dauer molt, during the dauer to L4 larval molt, and during the L4 to adult molt).
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 354
Relative score: 0.983 (Best raw score= for Gene )
Specificity index: 0.155
Wormbase (BLAST) RNAi primary
External "T28C6.6" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  W05B2.5 (col-93)
Description of "W05B2.5"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 83
Relative score: 0.231 (Best raw score= for Gene )
Specificity index: 0.036
External "W05B2.5" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  W05B2.1 (col-94)
Description of "W05B2.1"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 101
Relative score: 0.281 (Best raw score= for Gene )
Specificity index: 0.044
External "W05B2.1" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  B0222.6 (col-144)
Description of "B0222.6"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 240
Relative score: 0.667 (Best raw score= for Gene )
Specificity index: 0.105
External "B0222.6" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  F11G11.10 (col-17)
Description of "F11G11.10"  col-17 encodes a collagen which is expressed in all developmental stages except eggs, like col-15, col-16, and col-20; collagen genes with this expression pattern may be used for synthesis of cuticles after the L1 stage (e.g., the L4 cuticle).
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 175
Relative score: 0.486 (Best raw score= for Gene )
Specificity index: 0.077
External "F11G11.10" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  C29F4.1 (col-125)
Description of "C29F4.1"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 276
Relative score: 0.767 (Best raw score= for Gene )
Specificity index: 0.121
Wormbase (BLAST) RNAi primary
External "C29F4.1" Links  Wormbase NCBI Phenobank 1
Cenix:242-f8 Phenotypes Help with Phenotypes
Phenotype  Larval Lethal-Early (L1/L2)
Cenix:242-f8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:242-f8 (PCR_reagent)
Remark  post-embryonic: Larval Lethal-Early (L1/L2)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T15B7.3 Browse using GBrowse
Gene Graph
Gene Plot of T28C6.4 Browse using GBrowse
Gene Graph
Gene Plot of B0222.8 Browse using GBrowse
Gene Graph
Gene Plot of W05B2.6 Browse using GBrowse
Gene Graph
Gene Plot of T28C6.6 Browse using GBrowse
Gene Graph
Gene Plot of W05B2.5 Browse using GBrowse
Gene Graph
Gene Plot of W05B2.1 Browse using GBrowse
Gene Graph
Gene Plot of B0222.6 Browse using GBrowse
Gene Graph
Gene Plot of F11G11.10 Browse using GBrowse
Gene Graph
Gene Plot of C29F4.1 Browse using GBrowse
Gene Graph