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RNAi Experiment: Cenix:244-a4 Ace View of Cenix:244-a4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F42G8.4 (pmk-3)
Description of "F42G8.4"  pmk-3 encodes a homolog of p38, a mitogen-activated protein kinase (MAPK), activated in vitro by MEK6, indicating that it does respond like p38 to physiological stress; PMK-3 is expressed in nuclei throughout the intestine; PMK-3 is activated by osmotic stresses when heterologously expressed in mammalian cells; null mutants do not exhibit observable growth defects or hypersensitivity to several tested known stresses.
KOG Annotation  Mitogen-activated protein kinase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:8141939..8142265)
Transcript overlap: 249 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 228
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F42G8.4" Links  Wormbase NCBI Phenobank 1
Cenix:244-a4 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:244-a4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:244-a4 (PCR_reagent)
Remark  3/3 tests are wildtype
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F42G8.4 Browse using GBrowse
Gene Graph